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Writer's pictureRichard Yadon, RN

Non-Stimulant Options for ADHD Help: Exploring a New Path for Managing Symptoms



For anyone navigating life with ADHD, you know it’s rarely just about staying focused. Many people with ADHD also deal with what’s known as executive dysfunction, a set of challenges that go beyond typical ADHD symptoms. If you find it hard to manage time, stay organized, or control emotions, you might be experiencing executive dysfunction, which often doesn’t improve with standard ADHD stimulants. While medications like Adderall and Ritalin are effective for attention and focus, they don’t always address these deeper issues, and that’s where non-stimulant medications come in.


Understanding Executive Dysfunction and ADHD


When we think of ADHD, we usually picture restlessness, impulsivity, and a wandering mind. But ADHD can also interfere with “executive functions”—the skills that help us plan, organize, switch tasks, and regulate emotions. This is where many people with ADHD face hurdles, particularly with a process called “set-shifting.” Set-shifting is the ability to stop one task, switch to another, and return to the original task smoothly. For those with ADHD, a small interruption, like a five-minute break, can derail productivity for hours (Barkley, 2019). This goes beyond what stimulants like Adderall typically address.


Why Stimulants May Fall Short for Some


Stimulants are the most common treatment for ADHD and fall into two main types: amphetamines (such as Adderall and Vyvanse) and methylphenidate medications (like Ritalin and Concerta). These medications target the brain’s dopamine system, helping with focus and reducing impulsivity. However, while they make it easier to concentrate, they don’t necessarily improve executive functioning.


The issue with stimulants is that while they can create a strong sense of focus, this hyperfocus sometimes makes it harder to switch tasks effectively. Think of it as “tunnel vision”—you’re so locked in that interruptions become harder to manage. Once that hyperfocus is broken, it can feel like the train has derailed, and getting back on track isn’t easy (Brown, 2017). For people who experience these issues regularly, non-stimulants might provide a better solution.


Non-Stimulant Medications for ADHD Help


Non-stimulant medications offer an alternative for ADHD treatment, particularly for those who find stimulants ineffective or challenging. Currently, there are four primary non-stimulant options:


  1. Clonidine – Initially developed for high blood pressure, clonidine can reduce impulsivity in children with ADHD and is often used alongside stimulants (Posner et al., 2020).

  2. Guanfacine – Similar to clonidine, guanfacine has been used to target impulsivity and hyperactivity, particularly in children (Posner et al., 2020).

  3. Atomoxetine (Strattera) – This was the first non-stimulant approved by the FDA for treating ADHD in both children and adults. It works as a norepinephrine reuptake inhibitor, helping increase levels of this key neurotransmitter, which also indirectly boosts dopamine and serotonin (Pliszka, 2015).

  4. Viloxazine (Qelbree) – The newest option on the market, Qelbree has shown promise in treating ADHD symptoms in both children and adults without the common side effects associated with stimulants (Sallee, 2021).


How Non-Stimulants Support Executive Function


Unlike stimulants, which focus heavily on dopamine, non-stimulants like atomoxetine and viloxazine increase norepinephrine levels in the brain’s prefrontal cortex. This region is essential for executive functions, meaning that these non-stimulants can potentially support areas like time management, planning, and emotional control. In particular, viloxazine has shown promising results in improving executive dysfunction symptoms within weeks, especially in young people (Sallee, 2021).




Studies also indicate that Qelbree might work faster than other non-stimulants, with some people noticing improvements in one to two weeks (Sallee, 2021). This speed is encouraging for those who may have previously relied on stimulants and are looking for a quicker transition to non-stimulants. Another study revealed that after being stabilized on Qelbree, 85% of patients were able to reduce or even discontinue their stimulant use entirely (Posner et al., 2020).


Practical Considerations for Non-Stimulant ADHD Help


While non-stimulants offer promising benefits, there are some practical points to consider. As these are newer options, some insurance plans may require prior authorization, particularly with viloxazine. Additionally, some insurers may ask patients to try Strattera first before approving Qelbree. Despite these potential hurdles, many find the option of managing ADHD without the side effects of stimulants to be worth exploring.


If you’re looking for ADHD help and find that your current treatment plan isn’t fully addressing your symptoms, especially executive dysfunction, it may be worth discussing non-stimulant options with your doctor. Everyone’s ADHD experience is different, and exploring these alternatives could provide a path to a more comprehensive and personalized treatment plan.


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References

Barkley, R. A. (2019). Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. Guilford Press.


Brown, T. E. (2017). Smart But Stuck: Emotions in Teens and Adults with ADHD. John Wiley & Sons.


Pliszka, S. R. (2015). Practice Parameter for the Assessment and Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 50(9), 894-921.


Posner, J., Polanczyk, G. V., & Sonuga-Barke, E. (2020). Attention-deficit hyperactivity disorder. The Lancet, 395(10222), 1240-1250.


Sallee, F. R. (2021). Viloxazine extended-release capsules for the treatment of ADHD in pediatric patients: a review of pharmacology, efficacy, and safety. Expert Review of Neurotherapeutics, 21(1), 1-11.


The opinions and advice expressed in this and other content are purely for informational, entertainment, and educational purposes. Links to resources and products may provide our organization a referral fee. The information provided is not a substitute for professional advice, diagnosis, or treatment. If you or someone you know is experiencing any of the physical or mental health symptoms referred to in this or any other of our content, please consult with a trained medical professional or a licensed mental health provider.

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